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Article

Genetic heritability of ischemic stroke and the contribution of previously reported candidate gene and genomewide associations.

Stroke - 1 Dec 2012

Bevan Steve, Traylor Matthew, Adib-Samii Poneh, Malik Rainer, Paul Nicola L M, Jackson Caroline, Farrall Martin, Rothwell Peter M, Sudlow Cathie, Dichgans Martin, Markus Hugh S

Abstract excerpt

BACKGROUND AND PURPOSE: The contribution of genetics to stroke risk, and whether this differs for different stroke subtypes, remainsuncertain. Genomewide complex trait analysis allows heritability to be assessed from genomewide association study (GWAS) data. Previous candidate gene studies have identified many associations with stoke but whether these are important requires replication in large independent data...

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Source

Identifiers

PMID: 23042660
DOI: 10.1161/STROKEAHA.112.665760

Genes

PHACTR1
PITX2
ZFHX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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