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Article

Effect of PITX2 genetic variants on the susceptibility to stroke in the Chinese Han population.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2022

Zhao Weiwei, Hu Xiuxia, Hao Jie, Guo Le, Zhang Wenjie, Liu Jianfeng, Jin Tianbo, Gao Dakuan, Zhi Jin

Abstract excerpt

PURPOSE: Stroke is a multifactorial and complex disease caused by the obstruction or rupture of cerebrovascular. To explore the influence of genetic factors on stroke susceptibility, we investigated the association between four single nucleotide polymorphisms (SNPs) in the paired-like homeodomain transcription factor 2 (PITX2) gene and stroke risk. METHODS: A total of 977 volunteers including 476 stroke patients...

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PMID: 34990849
DOI: 10.1016/j.meegid.2021.105201

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