Article

Identification of 20 novel loci associated to ischemic stroke. Epigenome-Wide Association Study

2019-12-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> DNA methylation is dynamic, varies throughout the life course, and its levels are influenced by lifestyle and environmental factors, as well as by genetic variation. The leading genetic variants at stroke risk loci identified to date explain roughly 1–2% of stroke heritability. Most of these single nucleotide polymorphisms are situated within a regulatory sequence marked by D...

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Literature Corpus work: 618ee01f-d3ef-51fb-95df-081f1ff07d1a
DOI: 10.1101/2019.12.11.872945

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