Article
Identification of Novel Genetic Risk Variants Associated With Early-Onset Ischemic Stroke in Taiwan.
Neurology - 23 Jun 2026
Wang Yin-Cheng, Liu Kai-Ming, Gan Yu-Ling, Chi Nai-Fang, Lu Liang-Suei, Chou Che-Yu, Wang Liang-Yun, Chang Li-Hsin, Hou Ming-Chih, Fu Yun-Ching, Chiou Jeng-Fong, Wu Ming-Shiang, Yang Shun-Fa, Pang See-Tong, Wang Jaw-Yuan, Tsai Yi-Ting, Huang Chih-Yang, Chiu Kuan-Ming, Chen Ming, Chiang Fu-Tien, Wang Chih-Hung, Yao Wei-Jen, Lee Sing-Lian, Huang Chi-Hung, Liu Yo-Tsen, Wang Shuu-Jiun, Ko Wen-Ya, Chen Chien-Hsiun, Lee I-Hui
Abstract excerpt
BACKGROUND AND OBJECTIVES: Genome-wide association studies (GWASs) have identified common genetic risk loci for ischemic stroke (IS), primarily in European populations older than 55 years. We aimed to identify common and rare risk variants associated with early-onset IS (ages 18-54) in Taiwan. METHODS: We conducted GWASs of early-onset and all IS cases, compared with stroke-free controls of Han ethnicity, using...
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