Article
Genetic polymorphisms of cytochrome P450-1A2 (CYP1A2) among Emiratis.
PloS one - 1 Jan 2017
Al-Ahmad Mohammad M, Amir Naheed, Dhanasekaran Subramanian, John Anne, Abdulrazzaq Yousef M, Ali Bassam R, Bastaki Salim M A
Abstract excerpt
Cytochrome P450 1A2 (CYP1A2) is one of the CYP450 mixed-function oxidase system that is of clinical importance due to the large number of drug interactions associated with its induction and inhibition. In addition, significant inter-individual differences in the elimination of drugs metabolized by CYP1A2 enzyme have been observed which are largely due to the highly polymorphic nature of CYP1A2 gene. However,...
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