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Article

CYP2A6 and CYP2E1 polymorphisms in a Brazilian population living in Rio de Janeiro.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Feb 2006

Rossini A, Lima S Soares, Rapozo D C M, Faria M, Albano R M, Pinto L F Ribeiro

Abstract excerpt

Cytochrome P450 (CYP) is a superfamily of enzymes involved in the metabolism of endogenous compounds and xenobiotics. CYP2A6 catalyzes the oxidation of nicotine and the activation of carcinogens such as aflatoxin B1 and nitrosamines. CYP2E1 metabolizes ethanol and other low-molecular weight compounds and can also activate nitrosamines. The CYP2A6 and CYP2E1 genes are polymorphic, altering their catalytic...

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Identifiers

PMID: 16470306
DOI: 10.1590/s0100-879x2006000200005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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