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Article

High CYP2A6 enzyme activity as measured by a caffeine test and unique distribution of CYP2A6 variant alleles in Ethiopian population.

Omics : a journal of integrative biology - 1 Jul 2014

Aklillu Eleni, Djordjevic Natasa, Carrillo Juan Antonio, Makonnen Eyasu, Bertilsson Leif, Ingelman-Sundberg Magnus

Abstract excerpt

CYP2A6 metabolizes clinically relevant drugs, including antiretroviral and antimalarial drugs of major public health importance for the African populations. CYP2A6 genotype-phenotype relationship in African populations, and implications of geographic differences on enzyme activity, remain to be investigated. We evaluated the influence of CYP2A6 genotype, geographical differences, gender, and cigarette smoking on...

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Source

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Identifiers

PMID: 24380444
DOI: 10.1089/omi.2013.0140
PMCID: PMC4086241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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