Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High prevalence of CYP2A64 and CYP2A69 alleles detected among a Malaysian population.

Clinica chimica acta; international journal of clinical chemistry - 1 May 2009

Yusof Wardah, Gan Siew Hua

Abstract excerpt

BACKGROUND: CYP2A6 gene encodes the principal enzyme involved in the metabolism of many drugs including artesunate. We developed a simplified duplex nested PCR method for the detection of the CYP2A61B, CYP2A62, CYP2A64, CYP2A67, CYP2A68 and CYP2A69 variant alleles highly prevalent among Malaysian population. METHODS: Genomic DNA was isolated from peripheral blood of patients treated with artesunate by using a DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amodiaquine
Share to Antimalarials
Share to Artemisinins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Artesunate

Share to Cytochrome P-450 CYP2A6

Share to Drug-Related Side Effects and Adverse Reactions

Share to Malaysia

Share to Randomized Controlled Trials as Topic

Source

Identifiers

PMID: 19361454
DOI: 10.1016/j.cca.2009.01.032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High prevalence of CYP2A6*4 and CYP2A6*9 alleles detected among a Malaysian population.PMID 19361454Read ↗

Genetic polymorphism of CYP2C8 in three Malaysian ethnics: CYP2C8*2 and CYP2C8*3 are found in Malaysian Indians.Semantic proximity Read ↗

Pharmacogenetics of common SNP affecting drug metabolizing enzymes: comparison of allele frequencies between European and Malaysian/Singaporean.Semantic proximity Read ↗

Genetic polymorphism of CYP2D6 in Chinese subjects in Malaysia.Semantic proximity Read ↗

Heterogeneity of the CYP2D6 gene among Malays in Malaysia.Semantic proximity Read ↗

Genetic polymorphisms of CYP3A4: CYP3A4*18 allele is found in five healthy Malaysian subjects.Semantic proximity Read ↗

Inference of the Genetic Polymorphisms of CYP2D6 in Six Subtribes of the Malaysian Orang Asli from Whole-Genome Sequencing Data.Semantic proximity Read ↗

Allelic and genotype frequencies of major CYP2B6 polymorphisms in the Pakistani population.Semantic proximity Read ↗

Relationship between metabolic phenotypes and genotypes of CYP1A2 and CYP2A6 in the Nigerian population.Semantic proximity Read ↗

Allele and genotype frequencies of CYP2B6 in a Turkish population.Semantic proximity Read ↗

CYP2C9 polymorphism: prevalence in healthy and warfarin-treated Malay and Chinese in Malaysia.Semantic proximity Read ↗

Polymorphisms of UGT1A1*6, UGT1A1*27 & UGT1A1*28 in three major ethnic groups from Malaysia.Semantic proximity Read ↗

Detection of CYP2C19 Genetic Variants in Malaysian Orang Asli from Massively Parallel Sequencing Data.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.