Article
DNA mismatch repair and its many roles in eukaryotic cells.
Mutation research. Reviews in mutation research - 1 Jul 2017
Liu Dekang, Keijzers Guido, Rasmussen Lene Juel
Abstract excerpt
DNA mismatch repair (MMR) is an important DNA repair pathway that plays critical roles in DNA replication fidelity, mutation avoidance and genome stability, all of which contribute significantly to the viability of cells and organisms. MMR is widely-used as a diagnostic biomarker for human cancers in the clinic, and as a biomarker of cancer susceptibility in animal model systems. Prokaryotic MMR is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.