Article
The intricate interplay between MSI and polymorphisms of DNA repair enzymes in gastric cancer H.pylori associated.
Mutagenesis - 1 Jul 2017
Silva-Fernandes Isabelle Joyce de Lima, Oliveira Emanuele Silva de, Santos Juliana Carvalho, Ribeiro Marcelo Lima, Ferrasi Adriana Camargo, Pardini Maria Inês de Moura Campos, Burbano Rommel Mário Rodriguez, Rabenhorst Silvia Helena Barem
Abstract excerpt
Gastric cancer is the fourth most common type of cancer worldwide. Helicobacter pylori is a well-established risk factor and may cause injuries to genomic integrity through an inefficient DNA repair. This study aimed to examine the influence of polymorphisms in DNA repair enzymes using markers for microsatellite instability (MSI). Polymorphisms of DNA repair enzymes were detected by PCR-RFLP and MSI, by high...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
