Article
The association of Helicobacter pylori CagA EPIYA motifs and vacA genotypes with homologous recombination repair markers during the gastric precancerous cascade.
The International journal of biological markers - 1 Jun 2020
Mi Yang, Dong Haibin, Sun Xiangdong, Ren Feifei, Tang Youcai, Zheng Pengyuan
Abstract excerpt
BACKGROUND: Helicobacter pylori-induced DNA damage and impaired homologous recombination repair are vital molecular mechanisms for gastric cancer, which mainly count on its virulence factors cytotoxic-associated gene A (CagA) and vacuolating cytotoxin A (VacA). However, the relationship between H. pylori CagA EPIYA motifs and vacA genotypes with DNA damage and homologous recombination repair markers is still not...
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