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Helicobacter pylori infection modulates the expression of miRNAs associated with DNA mismatch repair pathway

16 Nov 2016

Abstract excerpt

Genetic and epigenetic inactivation of DNA mismatch repair (MMR) genes might lead to modifications in cancer-related gene expression and cancer development. Recently, it has been shown that the infection by Helicobacter pylori, the major causative agent of gastric cancer, induces DNA damage and inhibits MMR DNA repair. Also, it has been reported that microRNAs (miRs) have an important role in regulating genomic...

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PMID: 27862371
DOI: 10.1002/mc.22590

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