Article
Frequency and Clinicopathologic Features of RUNX1 Mutations in Patients With Acute Myeloid Leukemia Not Otherwise Specified.
American journal of clinical pathology - 1 Jul 2017
You Eunkyoung, Cho Young-Uk, Jang Seongsoo, Seo Eul-Ju, Lee Jung-Hee, Lee Je-Hwan, Lee Kyoo-Hyung, Koh Kyung-Nam, Im Ho Joon, Seo Jong Jin, Park Young-Mi, Lee Jong-Keuk, Park Chan-Jeoung
Abstract excerpt
OBJECTIVES: To evaluate the frequency and clinicopathologic characteristics of RUNX1 mutations, focusing on patients with acute myeloid leukemia not otherwise specified (AML NOS). METHODS: Diagnostic samples from 219 patients with AML NOS were analyzed for RUNX1 mutations using standard polymerase chain reaction and direct sequencing. RESULTS: Thirty-one RUNX1 mutations were detected in 33 (15.1%) patients....
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