Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Brain Biomarkers in Familial Alzheimer's Disease Mouse Models.

Journal of Alzheimer's disease : JAD - 1 Jan 2017

Kuttner-Hirshler Yafit, Venkatasubramanian Palamadai N, Apolinario Joan, Bonds Jacqueline, Wyrwicz Alice M, Lazarov Orly

Abstract excerpt

Alzheimer's disease (AD) is characterized by progressive loss of memory and cognitive deterioration. It is thought that the onset of the disease takes place several decades before memory deficits are apparent. Reliable biomarkers for the diagnosis or prognostication of the disease are highly desirable. Neural stem cells (NSC) exist in the adult brain throughout life and give rise to neural progenitor cells (NPC),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Cell Culture Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Mice, Transgenic

Share to Neural Stem Cells

Share to Neurogenesis

Share to Neurons

Share to Proton Magnetic Resonance Spectroscopy

Source

Open in PubMed Open full text

Identifiers

PMID: 28922152
DOI: 10.3233/JAD-170269
PMCID: PMC5783303

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Brain Biomarkers in Familial Alzheimer's Disease Mouse Models.PMID 28922152Read ↗

Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease.Semantic proximity Read ↗

Impaired neurogenesis is an early event in the etiology of familial Alzheimer's disease in transgenic mice.Semantic proximity Read ↗

Adult Human Neurogenesis in Alzheimer's Disease: Are New Neurons Being still Generated?Semantic proximity Read ↗

Monitoring disease progression in transgenic mouse models of Alzheimer's disease with proton magnetic resonance spectroscopySemantic proximity Read ↗

Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimer’s DiseaseSemantic proximity Read ↗

Impairments in neurogenesis are not tightly linked to depressive behavior in a transgenic mouse model of Alzheimer's disease.Semantic proximity Read ↗

Proton and Phosphorus Magnetic Resonance Spectroscopy of a Mouse Model of Alzheimer's DiseaseSemantic proximity Read ↗

The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice.Semantic proximity Read ↗

Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice.Semantic proximity Read ↗

Increased hippocampal neurogenesis in the progressive stage of Alzheimer's disease phenotype in an APP/PS1 double transgenic mouse model.Semantic proximity Read ↗

Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease.Semantic proximity Read ↗

Altered neurochemical profile in the McGill-R-Thy1-APP rat model of Alzheimer's disease: a longitudinal in vivo 1 H MRS study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.