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Article

Recent advances in genetic predisposition to pediatric acute lymphoblastic leukemia.

Expert review of hematology - 1 Jan 2020

Bloom Mackenzie, Maciaszek Jamie L, Clark Mary Egan, Pui Ching-Hon, Nichols Kim E

Abstract excerpt

Introduction: Historically, the majority of childhood cancers, including acute lymphoblastic leukemia (ALL), were not thought to have a hereditary basis. However, recent germline genomic studies have revealed that at least 5 - 10% of children with cancer (and approximately 3 - 4% of children with ALL) develop the disease due to an underlying genetic predisposition.Areas covered: This review discusses several...

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Identifiers

PMID: 31657974
DOI: 10.1080/17474086.2020.1685866
PMCID: PMC10576863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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