Regional evaluation of childhood acute lymphoblastic leukemia genetic susceptibility loci among Japanese.

doi:10.1038/s41598-017-19127-7

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Regional evaluation of childhood acute lymphoblastic leukemia genetic susceptibility loci among Japanese.

Scientific reports - 15 Jan 2018

Urayama Kevin Y, Takagi Masatoshi, Kawaguchi Takahisa, Matsuo Keitaro, Tanaka Yoichi, Ayukawa Yoko, Arakawa Yuki, Hasegawa Daisuke, Yuza Yuki, Kaneko Takashi, Noguchi Yasushi, Taneyama Yuichi, Ota Setsuo, Inukai Takeshi, Yanagimachi Masakatsu, Keino Dai, Koike Kazutoshi, Toyama Daisuke, Nakazawa Yozo, Kurosawa Hidemitsu, Nakamura Kozue, Moriwaki Koichi, Goto Hiroaki, Sekinaka Yujin, Morita Daisuke, Kato Motohiro, Takita Junko, Tanaka Toshihiro, Inazawa Johji, Koh Katsuyoshi, Ishida Yasushi, Ohara Akira, Mizutani Shuki, Matsuda Fumihiko, Manabe Atsushi

Abstract excerpt

Genome-wide association studies (GWAS) performed mostly in populations of European and Hispanic ancestry have confirmed an inherited genetic basis for childhood acute lymphoblastic leukemia (ALL), but these associations are less clear in other races/ethnicities. DNA samples from ALL patients (aged 0-19 years) previously enrolled onto a Tokyo Children's Cancer Study Group trial were collected during 2013-2015, and...

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PMID: 29335448
DOI: 10.1038/s41598-017-19127-7
PMCID: PMC5768812

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ELK3
IKZF1

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