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Article

Effects of PER3 clock gene polymorphisms on aging-related changes of the cerebral cortex.

Brain structure & function - 1 Mar 2018

Dewandre Delphine, Atienza Mercedes, Sanchez-Espinosa Mayely P, Cantero Jose L

Abstract excerpt

Considerable evidence suggests that circadian rhythmicity is progressively disrupted in senescence. Among clock genes, Period3 (PER3) has been associated with circadian phenotypes, homeostatic regulation of sleep, and cognitive performance in young adults. However, the effects of PER3 genotype on aging-related changes in both cognitive function and cortical integrity remain largely unknown. To shed light into...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28900721
DOI: 10.1007/s00429-017-1513-0

Genes

PER3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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