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Article

Reduced cortical thickness in hippocampal subregions among cognitively normal apolipoprotein E e4 carriers.

NeuroImage - 15 Jul 2008

Burggren A C, Zeineh M M, Ekstrom A D, Braskie M N, Thompson P M, Small G W, Bookheimer S Y

Abstract excerpt

Our objective was to investigate whether asymptomatic carriers of apolipoprotein E epsilon4 [APOE-4] demonstrate pathological differences and atrophy in medial temporal lobe (MTL) subregions. We measured cortical thickness and volume in MTL subregions (hippocampal CA fields 1, 2 and 3; dentate gyrus; entorhinal cortex; subiculum; perirhinal cortex; parahippocampal cortex; and fusiform gyrus) using a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18486492
DOI: 10.1016/j.neuroimage.2008.03.039
PMCID: PMC2601686

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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