Article
Early morning executive functioning during sleep deprivation is compromised by a PERIOD3 polymorphism.
Sleep - 1 Aug 2008
Groeger John A, Viola Antoine U, Lo June C Y, von Schantz Malcolm, Archer Simon N, Dijk Derk-Jan
Abstract excerpt
STUDY OBJECTIVES: To contrast the effects of total sleep deprivation (TSD) on executive and non-executive function in volunteers homozygous for either the short or long variant of a variable number tandem repeat polymorphism in PERIODS, which is a genetic marker for susceptibility to the negative effect of sleep loss on waking performance. DESIGN: Following two laboratory nights of baseline sleep, both groups...
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