Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Function of HLA-B*13:01 Involved in the Pathomechanism of Dapsone-Induced Severe Cutaneous Adverse Reactions.

The Journal of investigative dermatology - 1 Jul 2018

Chen Wei-Ti, Wang Chuang-Wei, Lu Chun-Wei, Chen Chun-Bing, Lee Hua-En, Hung Shuen-Iu, Choon Siew-Eng, Yang Chih-Hsun, Liu Ming-Tsan, Chen Ting Jui, Fan Wen-Lang, Su Shih-Chi, Lin Yang Yu-Wei, Chang Ya-Ching, Chung Wen-Hung

Abstract excerpt

Dapsone-induced hypersensitivity reactions may cause severe cutaneous adverse reactions, such as drug reaction with eosinophilia and systemic symptoms (DRESS). It has been reported that HLA-B*13:01 is strongly associated with dapsone-induced hypersensitivity reactions among leprosy patients. However, the phenotype specificity and detailed immune mechanism of HLA-B*13:01 remain unclear. We investigated the genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Differentiation, T-Lymphocyte
Share to Coculture Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dapsone

Share to Leprosy

Share to Malaysia

Share to T-Lymphocytes, Cytotoxic

Share to Taiwan

Source

Identifiers

PMID: 29458119
DOI: 10.1016/j.jid.2018.02.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Function of HLA-B*13:01 Involved in the Pathomechanism of Dapsone-Induced Severe Cutaneous Adverse Reactions.PMID 29458119Read ↗

Dapsone-induced severe cutaneous adverse drug reactions are strongly linked with HLA-B*13: 01 allele in the Thai population.Semantic proximity Read ↗

HLA-B*13 :01 Is a Predictive Marker of Dapsone-Induced Severe Cutaneous Adverse Reactions in Thai Patients.Semantic proximity Read ↗

The HLA-B*13:01 and the dapsone hypersensitivity syndrome in Korean and Asian populations: genotype- and meta-analyses.Semantic proximity Read ↗

Functional and structural characteristics of HLA-B*13:01-mediated specific T cells reaction in dapsone-induced drug hypersensitivitySemantic proximity Read ↗

Amino Acid Variants of HLA-DRB1 Confer Susceptibility to Dapsone Hypersensitivity Syndrome in Addition to HLA-B*13:01.Semantic proximity Read ↗

Association Between HLA-B*1301 and Dapsone-Induced Cutaneous Adverse Drug Reactions: A Systematic Review and Meta-analysis.Semantic proximity Read ↗

HLA-B*13:01 and the dapsone hypersensitivity syndrome.Semantic proximity Read ↗

A Review on Dapsone Hypersensitivity Syndrome Among Chinese Patients with an Emphasis on Preventing Adverse Drug Reactions with Genetic Testing.Semantic proximity Read ↗

Validation study of HLA-B*13:01 as a biomarker of dapsone hypersensitivity syndrome in leprosy patients in Indonesia.Semantic proximity Read ↗

HLA-restricted Biology of Severe Cutaneous Adverse Reactions (SCARs): Dapsone-induced Hypersensitivity as an ExampleSemantic proximity Read ↗

Validation Study of HLA-B*13:01 as a Biomarker of Dapsone Hypersensitivity Syndrome in Leprosy Patients in IndonesiaSemantic proximity Read ↗

Genetic associations of human leukocyte antigen alleles in cutaneous delayed drug hypersensitivity reactions: An updated reviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.