Article
The HLA-B*13:01 and the dapsone hypersensitivity syndrome in Korean and Asian populations: genotype- and meta-analyses.
Expert opinion on drug safety - 1 Oct 2020
Park Hye Jung, Park Jung-Won, Kim Sae Hoon, Choi So-Yun, Kim Hee-Kyoo, Jung Chang-Gyu, Yang Min-Suk, Kang Dong Yoon, Cho Min-Kyoung, Kwon Hyouk-Soo, Kang Hye-Ryun, Lee Yong Won
Abstract excerpt
BACKGROUND: The human leukocyte antigen (HLA)-B*13:01 was reported as an important risk factor for dapsone hypersensitivity syndrome (DHS) in Chinese and Thai populations. RESEARCH DESIGN AND METHODS: From the Korean nationwide registry, seven subjects with previous DHS were included. Their HLA allele/phenotype frequencies were compared with 8 dapsone-tolerant subjects recruited from a single institution, and...
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