Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence of Drug-Resistant Minority Variants in Untreated HIV-1-Infected Individuals With and Those Without Transmitted Drug Resistance Detected by Sanger Sequencing.

The Journal of infectious diseases - 1 Aug 2017

Clutter Dana S, Zhou Shuntai, Varghese Vici, Rhee Soo-Yon, Pinsky Benjamin A, Jeffrey Fessel W, Klein Daniel B, Spielvogel Ean, Holmes Susan P, Hurley Leo B, Silverberg Michael J, Swanstrom Ronald, Shafer Robert W

Abstract excerpt

Minority variant human immunodeficiency virus type 1 (HIV-1) nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance mutations are associated with an increased risk of virological failure during treatment with NNRTI-containing regimens. To determine whether individuals to whom variants with isolated NNRTI-associated drug resistance were transmitted are at increased risk of virological failure during...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD4 Lymphocyte Count
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV/AIDS drug development and treatment

Share to HIV Infections

Share to Mutation

Share to Reverse Transcriptase Inhibitors

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 28859436
DOI: 10.1093/infdis/jix338
PMCID: PMC5853472

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence of Drug-Resistant Minority Variants in Untreated HIV-1-Infected Individuals With and Those Without Transmitted Drug Resistance Detected by Sanger Sequencing.PMID 28859436Read ↗

Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naïve populations and associate with reduced treatment efficacy.Semantic proximity Read ↗

Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis.Semantic proximity Read ↗

Next-generation sequencing reveals major and minority HIV-1 drug resistance mutations in treatment-experienced individuals with virological failure.Semantic proximity Read ↗

Minority variants of drug-resistant HIV.Semantic proximity Read ↗

Impact of minority nonnucleoside reverse transcriptase inhibitor resistance mutations on resistance genotype after virologic failure.Semantic proximity Read ↗

Longitudinal Detection and Persistence of Minority Drug-Resistant Populations and Their Effect on Salvage Therapy.Semantic proximity Read ↗

Clinical implications of HIV-1 minority variants.Semantic proximity Read ↗

Minority variants associated with transmitted and acquired HIV-1 nonnucleoside reverse transcriptase inhibitor resistance: implications for the use of second-generation nonnucleoside reverse transcriptase inhibitors.Semantic proximity Read ↗

The Role of HIV-1 Drug-Resistant Minority Variants in Treatment FailureSemantic proximity Read ↗

Impact of Human Immunodeficiency Virus Type 1 Minority Variants on the Virus Response to a Rilpivirine-Based First-line Regimen.Semantic proximity Read ↗

Contribution of human immunodeficiency virus type 1 minority variants to reduced drug susceptibility in patients on an integrase strand transfer inhibitor-based therapy.Semantic proximity Read ↗

Primary HIV-1 Drug Resistant Minority Variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.