Article
Impact of minority nonnucleoside reverse transcriptase inhibitor resistance mutations on resistance genotype after virologic failure.
The Journal of infectious diseases - 15 Mar 2013
Li Jonathan Z, Paredes Roger, Ribaudo Heather J, Kozal Michael J, Svarovskaia Evguenia S, Johnson Jeffrey A, Geretti Anna Maria, Metzner Karin J, Jakobsen Martin R, Hullsiek Katherine Huppler, Ostergaard Lars, Miller Michael D, Kuritzkes Daniel R
Abstract excerpt
Drug-resistant human immunodeficiency virus type 1 (HIV-1) minority variants increase the risk of virologic failure for first-line nonnucleoside reverse transcriptase inhibitor (NNRTI)-based regimens. We performed a pooled analysis to evaluate the relationship between NNRTI-resistant minority var...
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