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Article

Prevalence of thiopurine S-methyltransferase gene polymorphisms in patients with inflammatory bowel disease from the island of Crete, Greece.

European journal of gastroenterology & hepatology - 1 Nov 2017

Coucoutsi Constantina, Emmanouil George, Goulielmos George, Sfakianaki Ourania, Koutroubakis Ioannis E, Kouroumalis Elias A

Abstract excerpt

BACKGROUND: There is evidence that genotyping for the thiopurine S-methyltransferase (TPMT) gene variants is useful for the prediction of response to thiopurine analogs (azathioprine and 6-mercaptopurine) in patients with inflammatory bowel disease (IBD). The aim of the present study was to determine the prevalence of TPMT gene polymorphisms in a genetic homogenous population of IBD patients in Crete and to...

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Identifiers

PMID: 28857898
DOI: 10.1097/MEG.0000000000000947

Genes

TPMT

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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