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Article

Prevalence of mutations in thiopurine S-methyltransferase gene among Slovak IBD patients.

Bratislavske lekarske listy - 1 Jan 2013

Desatova B, Hlavaty T, Balakova D, Pav I, Celec P, Gregus M, Zakuciova M, Hlista M, Horakova M, Kadasi L, Huorka M, Batovsky M

Abstract excerpt

BACKGROUND: Thiopurine S-methyltransferase (TPMT) plays an important role in the metabolism of thiopurines. It has been suggested that TPMT genetic polymorphisms lead to dose-related hematopoietic toxicity. Since there are major ethnic differences in the prevalence of particular TPMT variants, it is important for each country to study their own prevalence in order to estimate the role of TPMT variants-related...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23731044
DOI: 10.4149/bll_2013_069

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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