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Article

Combined effect of genetic polymorphisms of AURKA and environmental factors on oral cancer development in Taiwan.

PloS one - 1 Jan 2017

Chou Chia-Hsuan, Chou Ying-Erh, Chuang Chun-Yi, Yang Shun-Fa, Lin Chiao-Wen

Abstract excerpt

BACKGROUND: Oral squamous cell carcinoma (OSCC) is the sixth and fourth most common cause of cancer death in men worldwide and in Taiwan, respectively. AURKA, which encodes a centrosome-related serine/threonine kinase, is frequently amplified and overexpressed in many human cancers, particularly advanced OSCC. We conducted a hospital-based case-control study to estimate AURKA single-nucleotide polymorphisms...

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Identifiers

PMID: 28152093
DOI: 10.1371/journal.pone.0171583
PMCID: PMC5289639

Genes

AURKA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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