Epigenome-Wide Association Study Identifies Cardiac Gene Patterning and a Novel Class of Biomarkers for Heart Failure.

doi:10.1161/CIRCULATIONAHA.117.027355

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Article

Epigenome-Wide Association Study Identifies Cardiac Gene Patterning and a Novel Class of Biomarkers for Heart Failure.

Circulation - 17 Oct 2017

Meder Benjamin, Haas Jan, Sedaghat-Hamedani Farbod, Kayvanpour Elham, Frese Karen, Lai Alan, Nietsch Rouven, Scheiner Christina, Mester Stefan, Bordalo Diana Martins, Amr Ali, Dietrich Carsten, Pils Dietmar, Siede Dominik, Hund Hauke, Bauer Andrea, Holzer Daniel Benjamin, Ruhparwar Arjang, Mueller-Hennessen Matthias, Weichenhan Dieter, Plass Christoph, Weis Tanja, Backs Johannes, Wuerstle Maximilian, Keller Andreas, Katus Hugo A, Posch Andreas E

Abstract excerpt

BACKGROUND: Biochemical DNA modification resembles a crucial regulatory layer among genetic information, environmental factors, and the transcriptome. To identify epigenetic susceptibility regions and novel biomarkers linked to myocardial dysfunction and heart failure, we performed the first multi-omics study in myocardial tissue and blood of patients with dilated cardiomyopathy and controls. METHODS: Infinium...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28838933
DOI: 10.1161/CIRCULATIONAHA.117.027355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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