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Epigenome-wide association study for dilated cardiomyopathy in left ventricular heart tissue identifies putative gene sets associated with cardiac development and early indicators of cardiac risk

2024-12-04

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Methylation changes linked to dilated cardiomyopathy (DCM) affect cardiac gene expression. We investigate DCM mechanisms regulated by CpG methylation using multi-omics and causal analyses in the largest cohort of left ventricular tissues available. <bold>Methods: </bold>We mapped DNA methylation at ~850,000 CpG sites, performed array-based genotyping and RNA seq...

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Literature Corpus work
8893a7a7-be51-562b-bd34-4dd24d307fbf
DOI
10.21203/rs.3.rs-5141306/v1
Open publication

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Epigenome-wide association study for dilated cardiomyopathy in left ventricular heart tissue identifies putative gene sets associated with cardiac development and early indicators of cardiac riskDOI 10.21203/rs.3.rs-5141306/v1
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