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Integrative DNA methylome and transcriptome analysis identify potential genes on the influence of dilated cardiomyopathy-associated heart failure

28 Apr 2025

Abstract excerpt

OBJECTIVE: Dilated cardiomyopathy (DCM)-associated heart failure (HF) presents a significant clinical challenge, underlying epigenetic mechanisms remaining poorly understood. This study aims to investigate the interplay between DNA methylation and gene expression in the hearts of patients with DCM-associated HF (DCM-HF). METHODS: Atrial tissues were collected from five healthy donors and five heart transplant...

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PMID: 40296161
DOI: 10.1186/s13148-025-01876-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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