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Article

Leveraging clinical epigenetics in heart failure with preserved ejection fraction: a call for individualized therapies

16 Mar 2021

Abstract excerpt

Described as the 'single largest unmet need in cardiovascular medicine', heart failure with preserved ejection fraction (HFpEF) remains an untreatable disease currently representing 65% of new heart failure diagnoses. HFpEF is more frequent among women and associates with a poor prognosis and unsustainable healthcare costs. Moreover, the variability in HFpEF phenotypes amplifies complexity and difficulties in the...

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PMID: 33948637
DOI: 10.1093/eurheartj/ehab197

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