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Article

Sensitive genotyping of mutations in the EGFR gene from NSCLC patients using PCR-GoldMag lateral flow device.

Scientific reports - 21 Aug 2017

Li Xian-Ying, Zhang Chao, Zhang Qin-Lu, Zhu Juan-Li, Liu Qian, Chen Ming-Wei, Yang Xue-Min, Hui Wen-Li, Cui Ya-Li

Abstract excerpt

Epidermal growth factor receptor (EGFR) mutations predict better outcomes with EGFR tyrosine kinase inhibitors in patients with non-small cell lung cancer (NSCLC). Most common activating mutations include in-frame deletion in exon 19 and L858R substitution in exon 21, which account for >90% of all EGFR mutations in NSCLC. In this study, a PCR-GoldMag lateral flow assay (PCR-GoldMag LFA) was developed for the...

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Identifiers

PMID: 28827701
DOI: 10.1038/s41598-017-08210-8
PMCID: PMC5566435

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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