Article
EGFR T751_I759delinsN Mutation in Exon19 Detected by NGS but Not by Real-Time PCR in a Heavily-Treated Patient with NSCLC.
International journal of molecular sciences - 3 Nov 2022
Chang Zi-Ting, Chan Tien-Ming, Wu Chiao-En
Abstract excerpt
The detection of driver gene mutations can determine appropriate treatment strategies for non-small cell lung cancer (NSCLC) by identifying the presence of an effective druggable target. Mutations in the gene encoding the epidermal growth factor receptor (EGFR) are common driver mutations in NSCLC that can be effectively targeted by the use of EGFR tyrosine kinase inhibitors (EGFR-TKIs). However, without the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
