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Article

A new rapid method for detecting epidermal growth factor receptor mutations in non-small cell lung cancer.

Oncology reports - 1 Mar 2015

Takata Miyako, Chikumi Hiroki, Matsunami Keiji, Kodani Masahiro, Sakamoto Tomohiro, Hashimoto Kazuhiro, Nakamoto Masaki, Okada Kensaku, Kitaura Tsuyoshi, Matsumoto Shingo, Kurai Jun, Yamasaki Akira, Igishi Tadashi, Burioka Naoto, Shimizu Eiji

Abstract excerpt

Mutations in the epidermal growth factor receptor (EGFR) gene are associated with a favorable clinical response to the EGFR tyrosine kinase inhibitors gefitinib and erlotinib in non-small cell lung cancer (NSCLC). We present here, a new method for the rapid detection of the two most common EGFR mutations (delE746-A750 and L858R) from clinical samples. The methodology involves the combination of newly designed...

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Identifiers

PMID: 25591975
DOI: 10.3892/or.2015.3716
PMCID: PMC4324484

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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