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Article

Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression.

eLife - 14 Aug 2017

Andergassen Daniel, Dotter Christoph P, Wenzel Daniel, Sigl Verena, Bammer Philipp C, Muckenhuber Markus, Mayer Daniela, Kulinski Tomasz M, Theussl Hans-Christian, Penninger Josef M, Bock Christoph, Barlow Denise P, Pauler Florian M, Hudson Quanah J

Abstract excerpt

To determine the dynamics of allelic-specific expression during mouse development, we analyzed RNA-seq data from 23 F1 tissues from different developmental stages, including 19 female tissues allowing X chromosome inactivation (XCI) escapers to also be detected. We demonstrate that allelic expression arising from genetic or epigenetic differences is highly tissue-specific. We find that tissue-specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28806168
DOI: 10.7554/eLife.25125
PMCID: PMC5555720

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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