Article
Dynamic allelic expression in mouse mammary glands across the adult developmental cycle.
Nucleic acids research - 5 Sept 2025
Hanin Geula, Costello Kevin R, Tavares Hugo, AlSulaiti Boshra, Patel Shrina, Edwards Carol A, Ferguson-Smith Anne C
Abstract excerpt
The mammary gland, which primarily develops postnatally, undergoes significant changes during pregnancy and lactation to facilitate milk production. Through the generation and analysis of 480 transcriptomes, we provide the most detailed allelic expression map of the mammary gland, cataloguing cell-type-specific expression from ex-vivo purified cell populations over 10 developmental stages, enabling comparative...
Read the complete abstract on PubMedTopics
- Animals
- Mammary Glands, Animal
- Female
- Mice
- Genomic Imprinting
- Gene Expression Regulation, Developmental