Article
Allelome.PRO, a pipeline to define allele-specific genomic features from high-throughput sequencing data.
Nucleic acids research - 2 Dec 2015
Andergassen Daniel, Dotter Christoph P, Kulinski Tomasz M, Guenzl Philipp M, Bammer Philipp C, Barlow Denise P, Pauler Florian M, Hudson Quanah J
Abstract excerpt
Detecting allelic biases from high-throughput sequencing data requires an approach that maximises sensitivity while minimizing false positives. Here, we present Allelome.PRO, an automated user-friendly bioinformatics pipeline, which uses high-throughput sequencing data from reciprocal crosses of two genetically distinct mouse strains to detect allele-specific expression and chromatin modifications. Allelome.PRO...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
