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Article

Prostate cancer risk variants of the HOXB genetic locus.

Scientific reports - 31 May 2021

Dupont William D, Breyer Joan P, Johnson Spenser H, Plummer W Dale, Smith Jeffrey R

Abstract excerpt

The G84E germline mutation of HOXB13 predisposes to prostate cancer and is clinically tested for familial cancer care. We investigated the HOXB locus to define a potentially broader contribution to prostate cancer heritability. We sought HOXB locus germline variants altering prostate cancer risk in three European-ancestry case-control study populations (combined 7812 cases and 5047 controls): the International...

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Identifiers

PMID: 34059701
DOI: 10.1038/s41598-021-89399-7
PMCID: PMC8167119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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