Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

C-terminal determinants of Kir4.2 channel expression.

The Journal of membrane biology - 1 Jan 2006

Pearson Wade L, Skatchkov Serguei N, Eaton Misty J, Nichols Colin G

Abstract excerpt

Inward rectifier potassium (Kir) channels serve important functional and modulatory roles in a wide variety of cells. While the activity of several members of this channel family are tightly regulated by intracellular messengers such as adenosine triphosphate, G proteins, protein kinases and pH, other members are tonically active and activity is controlled only by the expression level of the protein. In a number...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to Ion Channel Gating
Share to Membrane Potentials

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Oocytes

Share to Patch-Clamp Techniques

Share to Potassium Channels, Inwardly Rectifying

Share to Tyrosine

Share to Xenopus laevis

Source

Identifiers

PMID: 17468958
DOI: 10.1007/s00232-006-0058-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

C-terminal determinants of Kir4.2 channel expression.PMID 17468958Read ↗

C-terminal domain of Kv4.2 and associated KChIP2 interactions regulate functional expression and gating of Kv4.2.Semantic proximity Read ↗

Inwardly Rectifying Potassium Channel Kir2.1 and its “Kir-ious” Regulation by Protein Trafficking and Roles in Development and DiseaseSemantic proximity Read ↗

Interdomain cytoplasmic interactions govern the intracellular trafficking, gating, and modulation of the Kv2.1 channel.Semantic proximity Read ↗

Kir2.6 regulates the surface expression of Kir2.x inward rectifier potassium channels.Semantic proximity Read ↗

Biochemical, biophysical, and structural investigations of two mutants (C154Y and R312H) of the human Kir2.1 channel involved in the Andersen-Tawil syndromeSemantic proximity Read ↗

Dependence of KCC2 K-Cl cotransporter activity on a conserved carboxy terminus tyrosine residue.Semantic proximity Read ↗

Disease Associated Mutations in KIR Proteins Linked to Aberrant Inward Rectifier Channel Trafficking.Semantic proximity Read ↗

A Novel View on the Role of Intracellular Tails in Surface Delivery of the Potassium-Chloride Cotransporter KCC2.Semantic proximity Read ↗

Identification of amino acids within the P2X2 receptor C-terminus that regulate desensitization.Semantic proximity Read ↗

A novel regulatory locus of phosphorylation in the C terminus of the potassium chloride cotransporter KCC2 that interferes with N-ethylmaleimide or staurosporine-mediated activation.Semantic proximity Read ↗

The role of the cytoplasmic pore in inward rectification of Kir2.1 channels.Semantic proximity Read ↗

C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.