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Article

Proper ciliary assembly is critical for restricting Hedgehog signaling during early eye development in mice.

Developmental biology - 1 Oct 2017

Burnett Jacob B, Lupu Floria I, Eggenschwiler Jonathan T

Abstract excerpt

Patterning of the vertebrate eye into optic stalk, retinal pigment epithelium (RPE) and neural retina (NR) territories relies on a number of signaling pathways, but how these signals are interpreted by optic progenitors is not well understood. The primary cilium is a microtubule-based organelle that is essential for Hedgehog (Hh) signaling, but it has also been implicated in the regulation of other signaling...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28778798
DOI: 10.1016/j.ydbio.2017.07.012
PMCID: PMC6544053

Genes

RPE
GLI2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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