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Article

IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.

Development (Cambridge, England) - 15 Apr 2017

Xin Daisy, Christopher Kasey J, Zeng Lewie, Kong Yong, Weatherbee Scott D

Abstract excerpt

Cilia are key regulators of animal development and depend on intraflagellar transport (IFT) proteins for their formation and function, yet the roles of individual IFT proteins remain unclear. We examined the Ift56hop mouse mutant and reveal novel insight into the function of IFT56, a poorly understood IFTB protein. Ift56hop mice have normal cilia distribution but display defective cilia structure, including...

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Source

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Identifiers

PMID: 28264835
DOI: 10.1242/dev.143255
PMCID: PMC5399663

Genes

IFT56
IFT27
IFT81
IFT88

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.PMID 28264835Read ↗

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