Article

Kinesin KIF18A is a novel PUM regulated target promoting mitotic progression and survival of human male germ cell line - TCam-2

2019-10-25

Abstract excerpt

<h4>ABSTRACT</h4> Regulation of proliferation, apoptosis and cell cycle is crucial for the physiology of germ cells. Their malfunction contributes to infertility and germ cell tumours. Kinesin KIF18A is an important germ cell specific regulator which downregulates apoptosis while promoting cell proliferation in animal models. Whereas regulation of KIF18A expression was studied at the transcriptional level, its po...

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Literature Corpus work: 2de0656b-6da1-505d-8e6b-e2e6e56f3800
DOI: 10.1101/819839

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