Article
Polymorphisms in Epithelial-Mesenchymal Transition-Related Genes and the Prognosis of Surgically Treated Non-small Cell Lung Cancer.
Annals of surgical oncology - 1 Oct 2017
Seok Yangki, Kang Hyo-Gyoung, Lee Shin Yup, Jeong Ji Yun, Choi Jin Eun, Jung Deuk Kju, Jin Cheng Cheng, Hong Mi Jeong, Do Sook Kyung, Lee Won Kee, Park Ji Young, Shin Kyung Min, Yoo Seung Soo, Lee Jaehee, Cho Sukki, Cha Seung Ick, Kim Chang Ho, Jheon Sanghoon, Lee Eung Bae, Park Jae Yong
Abstract excerpt
BACKGROUND: This study was conducted to determine whether single-nucleotide polymorphisms (SNPs) in EMT-related genes may influence the prognosis of NSCLC after surgery. METHODS: There were 88 SNPs in EMT-related genes evaluated in a discovery set of 376 patients who underwent curative surgery for NSCLC. Significantly, 14 SNPs were evaluated in a validation set of 428 patients. Luciferase assay and RT-PCR were...
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