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Article

Polymorphisms in genes related to epithelial-mesenchymal transition and risk of non-small cell lung cancer.

Carcinogenesis - 1 Oct 2017

Xie Kunlin, Ye Yuanqing, Zeng Yong, Gu Jian, Yang Hushan, Wu Xifeng

Abstract excerpt

The epithelial-mesenchymal transition (EMT) process is a crucial step for tumor invasion and metastasis. Previous research investigating EMT has mostly focused on its role in cancer progression. Recent studies showed that EMT and EMT-driving transcription factor (EMT-TF) expression are early events in lung cancer pathogenesis, implying a potential association between EMT and lung cancer risk. In this study, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28968839
DOI: 10.1093/carcin/bgx079
PMCID: PMC5862248

Genes

ADGRF1
NOTCH3
CDH1
EGFR
SMAD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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