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Article

Genetic variants of the Wnt signaling pathway as predictors of recurrence and survival in early-stage non-small cell lung cancer patients.

Carcinogenesis - 1 Jun 2014

Coscio Angela, Chang David W, Roth Jack A, Ye Yuanqing, Gu Jian, Yang Ping, Wu Xifeng

Abstract excerpt

Early-stage non-small cell lung cancer (NSCLC) is potentially curative. Nevertheless, many patients will show disease recurrence after curative treatment. The Wnt signaling pathway is a developmental and stem cell pathway that plays an important role in tumorigenesis and may affect cancer progression. We hypothesize that genetic variants of the Wnt pathway may influence clinical outcome in early-stage NSCLC...

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Source

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Identifiers

PMID: 24517998
DOI: 10.1093/carcin/bgu034
PMCID: PMC4043238

Genes

FZD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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