Genetic Polymorphisms in Activating Transcription Factor 3 Binding Site and the Prognosis of Early-Stage Non-Small Cell Lung Cancer.

doi:10.1159/000514131

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Article

Genetic Polymorphisms in Activating Transcription Factor 3 Binding Site and the Prognosis of Early-Stage Non-Small Cell Lung Cancer.

Oncology - 1 Jan 2021

Kang Hyo-Gyoung, Park Ji Eun, Lee Shin Yup, Choi Jin Eun, Do Sook Kyung, Hong Mi Jeong, Lee Jang Hyuck, Jeong Ji Yun, Do Young Woo, Lee Eung Bae, Shin Kyung Min, Lee Won Ki, Choi Sun Ha, Lee Yong Hoon, Seo Hye Won, Yoo Seung Soo, Lee Jaehee, Cha Seung Ick, Kim Chang Ho, Cho Sukki, Jheon Sanghoon, Park Jae Yong

Abstract excerpt

BACKGROUND: Activating transcription factor 3 (ATF3) plays a significant role in cancer development and progression. We investigated the association between variants in expression quantitative trait loci (eQTLs) within ATF3 binding regions and the prognosis of non-small cell lung cancer (NSCLC) after surgery. METHODS: A total of 772 patients with NSCLC who underwent curative surgery were enrolled. Using a public...

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PMID: 33626541
DOI: 10.1159/000514131

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