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Article

Molecular characteristics of the KCNJ5 mutated aldosterone-producing adenomas.

Endocrine-related cancer - 1 Oct 2017

Murakami Masanori, Yoshimoto Takanobu, Nakabayashi Kazuhiko, Nakano Yujiro, Fukaishi Takahiro, Tsuchiya Kyoichiro, Minami Isao, Bouchi Ryotaro, Okamura Kohji, Fujii Yasuhisa, Hashimoto Koshi, Hata Ken-Ichiro, Kihara Kazunori, Ogawa Yoshihiro

Abstract excerpt

The pathophysiology of aldosterone-producing adenomas (APAs) has been investigated via genetic approaches and the pathogenic significance of a series of somatic mutations, including KCNJ5, has been uncovered. However, how the mutational status of an APA is associated with its molecular characteristics, including its transcriptome and methylome, has not been fully understood. This study was undertaken to explore...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28747387
DOI: 10.1530/ERC-17-0117

Genes

KCNJ5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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