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Article

Integration of transcriptome and methylome analysis of aldosterone-producing adenomas

7 May 2015

Abstract excerpt

OBJECTIVE: The pathophysiology of aldosterone-producing adenomas (APA) has been investigated intensively through genetic and genomic approaches. However, the role of epigenetics in APA is not fully understood. In the present study, we explored the relationship between gene expression and DNA methylation status in APA. METHODS: We conducted an integrated analysis of transcriptome and methylome data of paired...

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PMID: 25953827
DOI: 10.1530/eje-15-0148

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