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Article

Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes.

Scientific reports - 20 Jul 2017

Jäger Susanne, Wahl Simone, Kröger Janine, Sharma Sapna, Hoffmann Per, Floegel Anna, Pischon Tobias, Prehn Cornelia, Adamski Jerzy, Müller-Nurasyid Martina, Waldenberger Melanie, Strauch Konstantin, Peters Annette, Gieger Christian, Suhre Karsten, Grallert Harald, Boeing Heiner, Schulze Matthias B, Meidtner Karina

Abstract excerpt

Diabetes-associated metabolites may aid the identification of new risk variants for type 2 diabetes. Using targeted metabolomics within a subsample of the German EPIC-Potsdam study (n = 2500), we tested previously published SNPs for their association with diabetes-associated metabolites and conducted an additional exploratory analysis using data from the exome chip including replication within 2,692 individuals...

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Share to Delta-5 Fatty Acid Desaturase
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Metabolome

Share to Metabolomics

Share to Oligonucleotide Array Sequence Analysis

Share to Quantitative Trait, Heritable

Share to Quantitative Trait Loci

Source

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Identifiers

PMID: 28729637
DOI: 10.1038/s41598-017-06158-3
PMCID: PMC5519666

Genes

BIN1
FADS1
GFRAL
MOGAT2
TFRC

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