Article
Metabolomics platforms for genome wide association studies--linking the genome to the metabolome.
Current opinion in biotechnology - 1 Feb 2013
Adamski Jerzy, Suhre Karsten
Abstract excerpt
Genome-wide association studies (GWAS) reveal links between genetic variance and predisposition to disease. With the advent of modern 'omics-technologies', GWAS can now identify the genetic factors that influence intermediate traits on pathways to disease, such as blood concentrations of carbohydrates, lipids, amino acids, and secondary metabolites, hormones and signal molecules. At the example of recent GWAS...
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