Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Experimental evidence reveals the UCP1 genotype changes the oxygen consumption attributed to non-shivering thermogenesis in humans.

Scientific reports - 17 Jul 2017

Nishimura Takayuki, Katsumura Takafumi, Motoi Midori, Oota Hiroki, Watanuki Shigeki

Abstract excerpt

Humans have spread out all over the world adapting to many different cold environments. Recent worldwide genome analyses and animal experiments have reported dozens of genes associated with cold adaptation. The uncoupling protein 1 (UCP1) gene enhances thermogenesis reaction in a physiological process by blocking ATP (adenosine triphosphate) synthesis on a mitochondrial membrane in brown adipose tissues. To our...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Biological
Share to Body Temperature

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cold Temperature

Share to Evolution, Molecular

Share to Haplotypes

Share to Oxygen Consumption

Share to Thermogenesis

Share to Uncoupling Protein 1

Source

Open in PubMed Open full text

Identifiers

PMID: 28717127
DOI: 10.1038/s41598-017-05766-3
PMCID: PMC5514118

Genes

UCP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Experimental evidence reveals the UCP1 genotype changes the oxygen consumption attributed to non-shivering thermogenesis in humans.PMID 28717127Read ↗

Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis.Semantic proximity Read ↗

Population genetic analysis of the uncoupling proteins supports a role for UCP3 in human cold resistance.Semantic proximity Read ↗

The human uncoupling protein-1 gene (UCP1): present status and perspectives in obesity research.Semantic proximity Read ↗

Association of uncoupling protein (Ucp) gene polymorphisms with cardiometabolic diseases.Semantic proximity Read ↗

UCP1, the mitochondrial uncoupling protein of brown adipocyte: A personal contribution and a historical perspective.Semantic proximity Read ↗

Further support to the uncoupling-to-survive theory: the genetic variation of human UCP genes is associated with longevity.Semantic proximity Read ↗

The Role of Nonshivering Thermogenesis Genes on Leptin Levels Regulation in Residents of the Coldest Region of Siberia.Semantic proximity Read ↗

[Association of UCP1 rs1800592, UCP2 rs660339, and UCP3 rs1800849 polymorphisms with body mass index and lipid metabolism parameters in the indigenous population of the North of Western Siberia].Semantic proximity Read ↗

Two variants located in the upstream enhancer region of human UCP1 gene affect gene expression and are correlated with human longevity.Semantic proximity Read ↗

Recent advances in our understanding of brown and beige adipose tissue: the good fat that keeps you healthySemantic proximity Read ↗

The uncoupling protein 1 gene (UCP1) is disrupted in the pig lineage: a genetic explanation for poor thermoregulation in piglets.Semantic proximity Read ↗

Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.